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MPM-1

CAT: 0804-HY-151503Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151503Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MPM-1, a marine Eusynstyelamides mimic, is a potent anticancer agent. MPM-1 can rapidly kill cancer cells in vitro by inducing a necrosis-like death. MPM-1 has the ability to induce immunogenic cell death. MPM-1 causes perturbation of autophagy and lysosomal swelling in cancer cells[1].
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mpm-1.html
Solubility
10 mM in DMSO
Smiles
NCCCCN1C(N(C(C(CCCC2=CC=CC=C2)(C1=O)CCCC3=CC=CC=C3)=O)CCCCN)=O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Molecular Formula
C34H44F6N4O7
Molecular Weight
734.73
References & Citations
[1]Susannah von Hofsten, et al. The marine natural product mimic MPM-1 is cytolytic and induces DAMP release from human cancer cell lines. Sci Rep. 2022 Sep 16;12 (1) :15586.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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