SphK2-IN-2

• Description:

  SphK2-IN-2 (21g) is a potent and selective SphK2 inhibitor with an IC50 value of 0.23 μM[1].

• UNSPSC:

  12352005

• Target:

  SphK

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sphk2-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1C=C(C=N1)C2=CN(N=N2)CC3=CC=C(C=C3)C4=NOC(C[C@@H]5CCCN5C(N)=N)=N4.Cl

• Molecular Formula:

  C21H25ClN10O

• Molecular Weight:

  468.94

• References & Citations:

  [1]Vijai Kumar Reddy Tangadanchu, et al. Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors. Eur J Med Chem. 2020 Nov 15;206:112713.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2927429-60-3]