SIRT5 inhibitor 4

• UNSPSC Description:

  SIRT5 inhibitor 4 (compound 11) is a potent, selective SIRT5 inhibitor with IC50 values of 26.4 and >400μM for SIRT5 and other SIRT subtype, respectively[1].

• Target Antigen:

  Sirtuin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sirt5-inhibitor-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(NC(C=C1)=CC=C1C2=CSC(NC3=CC=C(C(O)=O)C(O)=C3)=N2)=O

• Molecular Weight:

  369.39

• References & Citations:

  [1]Han LY, et, al. Identification of 2-hydroxybenzoic acid derivatives as selective SIRT5 inhibitors. Eur.J.Med.Chem.2022 Jul 22, 114623

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  708992-34-1