Products for Research Use Only
RegisterLogin

ERK5-IN-4

CAT: 0804-HY-150606Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-150606Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ERK5-IN-4 (compound 34b) is a potent and selective inhibitor of extracellular signal-related kinase 5 (ERK5) . ERK5-IN-4 inhibits ERK5 (full-length) and truncated ERK5 (ERK5 ΔTAD) kinase activity in HEK293 cells with an IC50 of 77 nM and 300 nM, respectively[1].
CAS Number
1888305-17-6
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erk5-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C(C2=C(Cl)C=CC(Cl)=C2F)=O)=CN1)NC3=CN(C)N=C3
Molecular Formula
C16H11Cl2FN4O2
Molecular Weight
381.19
References & Citations
[1]Miller DC, et al. Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor. J Med Chem. 2022 May 12. 65 (9) :6513-6540.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK5

Related Products

CatalogName
HY-14403-01ERK5-IN-1
HY-128341-01ERK5-IN-2
HY-150605ERK5-IN-3
HY-156451-01ERK5-IN-6
HY-156450-01ERK5-IN-5
HY-176529ERK5 ligand-1
HY-P86354ERK5 Antibody (YA6046, Rabbit)
HY-P85724ERK5 Antibody (YA5416, Mouse)
HY-P84530-01ERK5 Antibody (YA4227, Mouse)
HY-P80122-01ERK5 Antibody (YA451, Rabbit)

Alternative Products

CatalogName
MBS5804329ERK5-IN-4
E8ET1612-7ERK5
GTR18075449-01ERK5 Antibody
BA6443-5ERK5-IN-2
T63268-01ERK5-IN-3
MBS3841500-01ERK5-IN-1
MBS8526753-01ERK5 protein
BA6454-25ERK5-IN-5

Popular Products