α-Glucosidase-IN-11

α-Glucosidase-IN-11

• CAS Number: 2411744-76-6
• UNSPSC Description: α-Glucosidase-IN-11 is a highly permeable competitive α-glucosidase inhibitor with the IC50 value of 0.56 μM. α-Glucosidase-IN-11 binds to Trp residues in α-glucosidase and regulates protein folding. α-Glucosidase-IN-11 can be used to regulate blood glucose levels[1].
• Target Antigen: Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-glucosidase-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(OCC)C1=CC=C(N2C(CO)=CC=C2/C=C3OC(C4=C\3C=C(C)NC4=O)=O)C=C1
• Molecular Weight: 420.41
• References & Citations: [1]Tania Luthra, et al. Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes. Eur J Med Chem. 2020 Feb 15;188:112034.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported