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AB10

CAT: 0804-HY-149855Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149855Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AB10 is a selective S1R antagonist. AB10 with Ki of 10, 165 nM for S1R and S2R, respectively. AB10 reverses the effect of Capsaicin caused pain in model[1].
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ab10.html
Solubility
10 mM in DMSO
Smiles
C1(CN(CC2=CC=CC=C2)C3)C3CCCN1CCCC4=CC=CC=C4
Molecular Formula
C23H30N2
Molecular Weight
334.50
References & Citations
[1]Dichiara M, et al. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands. ACS Chem Neurosci. 2023 May 17;14 (10) :1845-1858.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Sigma 1 Receptor; Sigma 2 Receptor

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