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AD186

CAT: 0804-HY-149853Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149853Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AD186 is a potent and selective S1R agonist with Kis of 2.7, 27 nM for S1R and S2R, respectively. AD186 fully reverses the antiallodynic effect of BD-1063.
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ad186.html
Solubility
10 mM in DMSO
Smiles
N1(CCC2=CC=CC=C2)CC3(CCN(CC4=CC=CC=C4)CC3)C1
Molecular Formula
C22H28N2
Molecular Weight
320.47
References & Citations
[1]Dichiara M, et al. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands. ACS Chem Neurosci. 2023 May 17;14 (10) :1845-1858.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Sigma 1 Receptor; Sigma 2 Receptor

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