PRO-F

• Description :

  PRO-F is a photoactivable H2S donor with ROS scavenging ability. PRO-F can be activated by light to produce fluorescent signal, for real-time tracking of released H2S. PRO-F activation doesn’t consume endogenous substances. deliver H2S in an intracellular environment to protect cells from excessive reactive oxygen species (ROS) induced damage. PRO-F shows enhancement on chronic wound healing, researched in diabetic models as well[1].

• UNSPSC :

  12171500

• Target :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/pro-f.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1(C)CC(/C=C/C2=CC=C(OC(OCC3=CC=C(OCC4=CC=CC=C4[N+]([O-])=O)C=C3)=S)C=C2)=C/C(C1)=C(C#N)/C#N

• Molecular Formula :

  C34H29N3O5S

• Molecular Weight :

  591.68

• References & Citations :

  [1]Yuan F, et al. Photoactivated Hydrogen Sulfide Donor with a Near-Infrared Fluorescence Report System for Accelerated Chronic Wound Healing. Anal Chem. 2023 May 2;95 (17) :6931-6939.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported