Bromodomain IN-2

• UNSPSC Description:

  Bromodomain IN-2 is a pan bromodomain (BD) inhibitor with KD values of 250, 420, 130, 430, 67, 240, 970 nM for BRD4(1), CBP, BRPF1B, BRD7, BRD9, BRDT(1), CECR2 respectively. Bromodomain IN-2 shows antiproliferative activity[1].

• Target Antigen:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bromodomain-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(C)NC(C3=C(Cl)C=CC(N)=C3)=C2CCCC1

• Molecular Weight:

  288.77

• References & Citations:

  [1]Warstat R, et al. A novel pan-selective bromodomain inhibitor for epigenetic drug design. Eur J Med Chem. 2023 Mar 5;249:115139.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2445335-77-1