Bromodomain IN-2

Bromodomain IN-2

• CAS Number: 2445335-77-1
• UNSPSC Description: Bromodomain IN-2 is a pan bromodomain (BD) inhibitor with KD values of 250, 420, 130, 430, 67, 240, 970 nM for BRD4(1), CBP, BRPF1B, BRD7, BRD9, BRDT(1), CECR2 respectively. Bromodomain IN-2 shows antiproliferative activity[1].
• Target Antigen: Epigenetic Reader Domain
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/bromodomain-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=C(C)NC(C3=C(Cl)C=CC(N)=C3)=C2CCCC1
• Molecular Weight: 288.77
• References & Citations: [1]Warstat R, et al. A novel pan-selective bromodomain inhibitor for epigenetic drug design. Eur J Med Chem. 2023 Mar 5;249:115139.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported