ATP Synthesis-IN-3

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804-HY-149736

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CAS Number: 3032416-36-4
UNSPSC Description: ATP Synthesis-IN-3 (compound 31) is an ATP hydrolysis inhibitor with protective effects during myocardial ischemia. ATP Synthesis-IN-3 can increase the ATP content of ischemic cardiomyocytes, increase the phosphorylation of PKA and phospholamban, and inhibit ischemia-induced apoptosis[1].
Target Antigen: ATP Synthase; PKA
Type: Reference compound
Related Pathways: Membrane Transporter/Ion Channel;Stem Cell/Wnt;TGF-beta/Smad
Applications: Neuroscience-Neuromodulation
Field of Research: Cardiovascular Disease
Assay Protocol: https://www.medchemexpress.com/atp-synthesis-in-3.html
Solubility: 10 mM in DMSO
Smiles: CN1CCN(C2=CC=C(NC3=NC(N4CCOCC4)=C5C(C(C6=CC=CC=C6)=NN5CC7=CC=C(C=C7)OC)=C3)C=C2)CC1
Molecular Weight: 589.73
References & Citations: [1]Nikolaou PE et al. Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors. J Med Chem. 2023 Nov 23;66(22):15115-15140.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
T9978-50mg	Glutathione synthesis-IN-1
T9978-5mg	Glutathione synthesis-IN-1
T9978-1g	Glutathione synthesis-IN-1
T9978-1mg	Glutathione synthesis-IN-1
T9978-10mg	Glutathione synthesis-IN-1
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B24408	All-in-One cDNA Synthesis SuperMix
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