J6-3

• UNSPSC Description:

  J6-3 is an inhibitor of ICMT with an IC50 of 0.6 μM and has anticancer activity. J6-3 inhibits MDA-MB231 cells with an IC50 of 3.4 μM[1].

• Target Antigen:

  ICMT

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/j6-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCCCN1C(CN(CC)CC)=CC2=CC(C3=CC=C(C)C=C3)=CC=C12

• Molecular Weight:

  404.63

• References & Citations:

  [1]Yang WS et al. Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents. Amino Acids. 2017 Sep;49(9):1469-1485.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported