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α-Synuclein inhibitor 9

CAT: 0804-HY-149509Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149509Size:1 Each
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Description
α-Synuclein inhibitor 9 (Compound 20C) is an α-Synuclein inhibitor. α-Synuclein inhibitor 9 binds to cavities in mature α-synuclein fibrils and reduces the β-sheet structure. α-Synuclein inhibitor 9 inhibits A53T α-Syn aggregation. α-Synuclein inhibitor 9 has neuroprotective effect, improves brain functional connection and relieves motor dysfunction.α-Synuclein inhibitor 9 can be used for Parkinson’s disease (PD) research.[1].
CAS Number
1510825-03-2
UNSPSC
12352005
Target
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-synuclein-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(CC2=CC=C(C(CC3=CC=C(C(CC4=CC=C(C=C4)O)=C3)O)=C2)O)C=C1
Molecular Formula
C27H24O4
Molecular Weight
412.48
References & Citations
[1]Peng Y, et al. A small molecule 20C from Gastrodia elata inhibits α-synuclein aggregation and prevents progression of Parkinson's disease. Cell Death Dis. 2023 Sep 6;14 (9) :594.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation

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