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KN1022

CAT: 0804-HY-149462-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149462-01Size:1 mg
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Description
KN1022 an inhibitor of phosphorylation of platelet-derived growth factor receptor (PDGFR) with IC50 of 0.24 μM[1].
CAS Number
205255-11-4
UNSPSC
12352005
Target
PDGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/kn1022.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(CC1)C2=C3C=C(OC)C(OC)=CC3=NC=N2)NC4=CC=C([N+]([O-])=O)C=C4
Molecular Formula
C21H22N6O5
Molecular Weight
438.44
References & Citations
[1]Kenji Matsuno, et al. Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives. J Med Chem. 2002 Jul 4;45 (14) :3057-66.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T60110-01KN1022

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