HGAPDH-IN-1

CAT: 0804-HY-149076Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149076Size:1 Each
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Description
HGAPDH-IN-1, a 3-bromo-4,5-dihydroisoxazole derivative, is a specific and potent hGAPDH covalent inhibitor. hGAPDH-IN-1 reduces cancer cell growth in different pancreatic cancer cell lines.
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hgapdh-in-1.html
Solubility
10 mM in DMSO
Smiles
BrC1=NOC2(C1)CCCC3=C2C=CC=C3
Molecular Formula
C12H12BrNO
Molecular Weight
266.13
References & Citations
[1]Andrea Galbiati, et al. Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells. Eur J Med Chem. 2023 Apr 6;254:115286.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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