hGAPDH-IN-1

• UNSPSC Description:

  hGAPDH-IN-1, a 3-bromo-4,5-dihydroisoxazole derivative, is a specific and potent hGAPDH covalent inhibitor. hGAPDH-IN-1 reduces cancer cell growth in different pancreatic cancer cell lines.

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hgapdh-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  BrC1=NOC2(C1)CCCC3=C2C=CC=C3

• Molecular Weight:

  266.13

• References & Citations:

  [1]Andrea Galbiati, et al. Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells. Eur J Med Chem. 2023 Apr 6;254:115286.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported