AB-506

• Description :

  AB-506 is an orally active inhibitor of HBV replication targeting the viral core protein. AB-506 can bind to HBV core protein, accelerate capsid assembly and inhibit HBV pgRNA encapsidation. AB-506 can be used in chronic hepatitis B (CHB) research[1].

• CAS Number :

  [2245020-50-0]

• UNSPSC :

  12352005

• Target :

  HBV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ab-506.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC(C=C1NC(C2=C3C([C@H](CC3)NC(OCC4=NN(C)C=N4)=O)=C(C=C2)F)=O)=C(C=C1)F

• Molecular Formula :

  C21H18ClF2N5O3

• Molecular Weight :

  461.85

• References & Citations :

  [1]Nagraj Mani, et al. Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein. Antiviral Res. 2022 Jan;197:105211.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported