MCT1-IN-3

MCT1-IN-3

• CAS Number: 2878360-80-4
• UNSPSC Description: MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor with an IC50 value of 81.0 nM. MCT1-IN-3 has also significant inhibitivity against the multidrug transporter ABCB1. MCT1-IN-3 can be used for the research of cancer[1].
• Target Antigen: Monocarboxylate Transporter; P-glycoprotein
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mct1-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: COC(/C(C#N)=C/C1=CN(C2=CC=CC=C12)CC(NC3=CC=C(C=C3)OC)=O)=O
• Molecular Weight: 389.40
• References & Citations: [1]Sachin Puri, et al. Indole Derivatives as New Structural Class of Potent and Antiproliferative Inhibitors of Monocarboxylate Transporter 1 (MCT1; SLC16A1). J Med Chem. 2023 Jan 12;66(1):657-676.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported