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NUCC-0223619

CAT: 0804-HY-148173Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-148173Size:1 Each
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Description
NUCC-0223619 is an IDO1 inhibitor, induce degradation of IDO protein. NUCC-0223619 can be used to synthesis PROTAC[1].
CAS Number
1923835-78-2
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nucc-0223619.html
Solubility
10 mM in DMSO
Smiles
FC1=CC2=C(C=C1)N=CC=C2[C@H](CC3)CC[C@@]3([H])[C@@H](C)C(NC(C=C4)=CC(O)=C4Cl)=O
Molecular Formula
C24H24ClFN2O2
Molecular Weight
426.91
References & Citations
[1]Schiltz Gary E, et al. Proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of indoleamine 2,3-dioxygenase (IDO) protein: United States, US20220023431. 2022-01-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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