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TbPTR1 inhibitor 1

CAT: 0804-HY-147940Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147940Size:1 Each
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Description
TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM) [1].
CAS Number
2499713-65-2
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tbptr1-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(N(CC)CC2=CN=C(N=C(N)N=C3N)C3=N2)C=C1)C4=CC=CC=C4
Molecular Formula
C22H21N7O
Molecular Weight
399.45
References & Citations
[1]Pöhner I, et al. Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. J Med Chem. 2022 Jun 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Trypanosoma

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