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Serum thymic factor (acetate)

CAT: 0804-HY-P3206A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P3206A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor. Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072) -induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases[1][2][3][4].
CAS Number
125117-65-9
Product Name Alternative
Thymulin (acetate) ; Thymic factor (acetate)
UNSPSC
12352209
Target
ERK
Type
Peptides
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/serum-thymic-factor-acetate.html
Purity
99.62
Solubility
H2O : ≥ 100 mg/mL
Smiles
NC(C[C@@H](C(O)=O)NC([C@H](CO)NC(CNC(CNC([C@H](CCC(N)=O)NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](C)NC([C@@H]1CCC(N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O
Molecular Formula
C35H58N12O17
Molecular Weight
918.91
References & Citations
[1]Pardo J, et al. Physiology, molecular biology and therapeutic potential of the thymic peptide thymulin[J]. Physiological Mini Reviews (PMR), 2012, 6.|[2]Dardenne M, et al. Role of thymulin or its analogue as a new analgesic molecule. Ann N Y Acad Sci. 2006 Nov;1088:153-63.|[3]Kohda Y, et al. Protective effect of serum thymic factor, FTS, on cephaloridine-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Nov;28 (11) :2087-91.|[4]Mizutani M, et al. In vivo administration of serum thymic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice. Arch Virol. 1996;141 (1) :73-83.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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