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K203

CAT: 0804-HY-146959Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146959Size:1 Each
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Description
K203 is a potent reactivator of tabun-inhibited AChE. K203 is a crucial antidote used for the organophosphate intoxication[1].
CAS Number
955034-69-2
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/k203.html
Solubility
10 mM in DMSO
Smiles
NC(C1=CC=[N+](C=C1)C/C=C/C[N+]2=CC=C(C=C2)/C=N/O)=O.[Br-].[Br-]
Molecular Formula
C16H18Br2N4O2
Molecular Weight
458.15
References & Citations
[1]Kamil Musilek, et al. Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E) -1- (4-carbamoylpyridinium) -4- (4-hydroxyiminomethylpyridinium) -but-2-ene dibromide (K203) . J Med Chem. 2007 Nov 1;50 (22) :5514-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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