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LmCPB-IN-1

CAT: 0804-HY-146649Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146649Size:1 Each
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Description
LmCPB-IN-1 (compound 35) is a potent and reversible covalent Leishmania mexicana cysteine protease B (LmCPB) inhibitor with a pKi of 9.7[1].
CAS Number
2151025-98-6
UNSPSC
12352005
Target
Cathepsin; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lmcpb-in-1.html
Solubility
10 mM in DMSO
Smiles
CC(C[C@@H](C(N(N(C#N)C)C)=O)NC(C1=CC(C(C)(C)C)=NN1C)=O)C
Molecular Formula
C18H30N6O2
Molecular Weight
362.47
References & Citations
[1]Jean F R Ribeiro, et al. Crystal structure of Leishmania mexicana cysteine protease B in complex with a high-affinity azadipeptide nitrile inhibitor. Bioorg Med Chem. 2020 Nov 15;28 (22) :115743.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania

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