Products for Research Use Only
RegisterLogin

Haspin-IN-2

CAT: 0804-HY-146587Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-146587Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Haspin-IN-2 (compound 4) is a potent and selective haspin inhibitor with an IC50 of 50 nM. Haspin-IN-1 also inbibits CLK1 and DYRK1A with IC50s of 445 nM and 917 nM, respectively[1].
CAS Number
2768474-47-9
UNSPSC
12352005
Target
CDK; DYRK; Haspin Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/haspin-in-2.html
Solubility
10 mM in DMSO
Smiles
COC1=NC2=C(C3=C(C=C2C=N1)C=NC=C3)[N+]([O-])=O
Molecular Formula
C12H8N4O3
Molecular Weight
256.22
References & Citations
[1]Wael Zeinyeh, et al. Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity. Eur J Med Chem. 2022 Jun 5;236:114369.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CLK; DYRK1

Related Products

CatalogName
HY-146636-01Haspin-IN-3
HY-146586Haspin-IN-1
HY-163858Haspin-IN-4
HY-RS06009HASPIN Human Pre-designed siRNA Set A
HY-RS06010Haspin Mouse Pre-designed siRNA Set A
HY-RS06011Haspin Rat Pre-designed siRNA Set A
HY-W011060-01Cryptand 2.2.2
HY-B1500-012,2,2-Trichloroethanol
HY-N2048-012,2':5',2''-Terthiophene
HY-W0733142,2,2-Trifluoroethoxyamine (hydrochloride)

Alternative Products

CatalogName
T60394-01Haspin-IN-2
T89382-01Haspin-IN-4
MBS9430599-01HASPIN Antibody
MBS5803206Haspin-IN-1
BUP01510-01Haspin-IN-3
E40PV1685HASPIN Antibody

Popular Products