GRP78-IN-2

• UNSPSC Description:

  GRP78-IN-2 (Compound FL5) is a GRP78 (Glucose Regulated Protein 78 kDa) inhibitor. GRP78-IN-2 preferentially targeting cell surface GRP78 and shows potent antiangiogenic and anticancer activities without affecting other normal cells[1].

• Target Antigen:

  HSP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/grp78-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC(OC)=CC(C(OCC2=CC=C(C=C2)C3=C(C4=CC=CC=C4O3)C(NCC(C)C)=O)=O)=C1

• Molecular Weight:

  487.54

• References & Citations:

  [1]Qiao Y, et al. Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy. Eur J Med Chem. 2020 May 1;193:112228.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1882875-63-9