GRP78-IN-1

CAT: 0804-HY-145857Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-145857Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GRP78-IN-1 exhibits several interactions with GRP78 residues with binding energy of -8.07 kcal/mol. GRP78-IN-1 shows the potent cytotoxic, anti-proliferative in cancer cells. GRP78-IN-1 exhibits promising apoptosis in breast cancer cells and stalls wound healing properties[1].
UNSPSC
12352005
Target
Apoptosis; HSP
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/grp78-in-1.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]12CC[C@]3(O[C@H]3[C@@]14OC(C(CC5=CC=C(C=C5)F)=C4CC[C@H]2C)=O)C
Molecular Formula
C21H23FO3
Molecular Weight
342.40
References & Citations
[1]Rasool JU, et al. Palladium catalyzed migratory heck coupling of arteannuin B and boronic acids: An approach towards the synthesis of antiproliferative agents in breast and lung cancer cells. Bioorg Chem. 2022, 122:105694.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP70

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