Tubulin polymerization-IN-21

Tubulin polymerization-IN-21

• CAS Number: 2703017-14-3
• UNSPSC Description: Tubulin polymerization-IN-21 (compound 9a) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-21 exhibits anti-cancer activity through disrupting cellular integrity and affecting glucose metabolism[1].
• Target Antigen: Microtubule/Tubulin
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Cancer; Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/tubulin-polymerization-in-21.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=C(OC)C(OC)=C1)/C=C/C2=CN(C)C3=C2C=C(C(C4=CC(OC)=C(OC)C(OC)=C4)=O)C=C3
• Molecular Weight: 515.55
• References & Citations: [1]Kode J, et, al. Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors. Bioorg Chem. 2020 Dec;105:104447.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported