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GABAA receptor agent 8

CAT: 0804-HY-146100Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146100Size:1 Each
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Description
GABAA receptor agent 8 (compoud 5e) is a potent GABAA receptor positive modulator. GABAA receptor agent 8 shows anticonvulsant activity in vitro and in vivo with low neurotoxicity. GABAA receptor agent 8 has the potential for the research of epilepsy[1].
CAS Number
2376841-54-0
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gabaa-receptor-agent-8.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(CC2=CC=CC=C2)N=C3N1NC(C4=CC=C(C)C=C4)=N3
Molecular Formula
C19H16N4O
Molecular Weight
316.36
References & Citations
[1]Huang L, et al. Discovery of [1,2,4]-triazolo [1,5-a]pyrimidine-7 (4H) -one derivatives as positive modulators of GABAA1 receptor with potent anticonvulsant activity and low toxicity. Eur J Med Chem. 2020 Jan 1;185:111824.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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