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L-Glutamic acid-13C2

CAT: 0804-HY-14608S10-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14608S10-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Glutamic acid-13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA) . L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].
CAS Number
115473-56-8
UNSPSC
12352211
Target
Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-glutamic-acid-13c2.html
Purity
99.7
Solubility
10 mM in DMSO
Smiles
OC(CC[13C@H](N)[13C](O)=O)=O
Molecular Formula
C3 13C2H9NO4
Molecular Weight
149.11
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6 (1) :73-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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