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HPV18-IN-1

CAT: 0804-HY-146033Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146033Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HPV18-IN-1 (Compound H1) is a potent inhibitor of HPV18. HPV18-IN-1 prevents cervical cancer cells from premature cell procession and abnormal proliferation. HPV18-IN-1 supresses E7-Rb-E2F cellular pathway and DNA methylation. HPV18-IN-1 has the potential for the research of cancer diseases[1].
CAS Number
331851-78-6
UNSPSC
12352005
Target
HPV
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpv18-in-1.html
Solubility
10 mM in DMSO
Smiles
NC1=CC=C(OC(C2=CC=C3N=C(N)SC3=C2)=N4)C4=C1
Molecular Formula
C14H10N4OS
Molecular Weight
282.32
References & Citations
[1]Sim S, et al. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorg Med Chem. 2021 Sep 15;46:116371.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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