HBV-IN-21

HBV-IN-21

• CAS Number: 2460957-52-0
• UNSPSC Description: HBV-IN-21 (Compound II-8b) is an HBV DNA replication inhibitor with an IC50 of 2.2 µM. HBV-IN-21 can interact HBV 4 capsid protein with good affinity (KD = 60.0 μM)[1].
• Target Antigen: DNA/RNA Synthesis; HBV
• Type: Reference compound
• Related Pathways: Anti-infection;Cell Cycle/DNA Damage
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/hbv-in-21.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=C(CC(C)C)SC(C2=NC=CS2)=N1)NNC3=CC=C(F)C=C3
• Molecular Weight: 376.47
• References & Citations: [1]Jia H, et al. Design, diversity-oriented synthesis and biological evaluation of novel heterocycle derivatives as non-nucleoside HBV capsid protein inhibitors. Eur J Med Chem. 2020 Sep 15;202:112495.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported