HBV-IN-21

CAT: 0804-HY-146011Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-146011Size:1 Each

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Description

HBV-IN-21 (Compound II-8b) is an HBV DNA replication inhibitor with an IC50 of 2.2 µM. HBV-IN-21 can interact HBV 4 capsid protein with good affinity (KD = 60.0 μM) [1].

CAS Number

2460957-52-0

UNSPSC

12352005

Target

DNA/RNA Synthesis; HBV

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hbv-in-21.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(CC(C)C)SC(C2=NC=CS2)=N1)NNC3=CC=C(F)C=C3

Molecular Formula

C17H17FN4OS2

Molecular Weight

376.47

References & Citations

[1]Jia H, et al. Design, diversity-oriented synthesis and biological evaluation of novel heterocycle derivatives as non-nucleoside HBV capsid protein inhibitors. Eur J Med Chem. 2020 Sep 15;202:112495.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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HBV-IN-21

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