HBV-IN-23

CAT: 0804-HY-146395Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-146395Size:1 Each

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Description

HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication with an IC50 of 0.58 μM. HBV-IN-23 inhibits HBV DNA replication in both agent sensitive and resistant HBV strains. HBV-IN-23 shows anti-hepatocellular carcinoma cell (HCC) activities. HBV-IN-23 induces HepG2 cells apoptosis[1].

CAS Number

2413649-89-3

UNSPSC

12352005

Target

Apoptosis; DNA/RNA Synthesis; HBV

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/hbv-in-23.html

Solubility

10 mM in DMSO

Smiles

CN(CCCOC1=CC=C2N=C(N(C(C2=C1)=O)CC3=CC=CO3)SCC4=CC=CC=C4)C

Molecular Formula

C25H27N3O3S

Molecular Weight

449.57

References & Citations

[1]Qiu J, et al. Discovery of novel quinazolinone derivatives as potential anti-HBV and anti-HCC agents. Eur J Med Chem. 2020 Nov 1;205:112581.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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