Ziprasidone (mesylate)

CAT: 0804-HY-14542CSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-14542CSize:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Ziprasidone (CP-88059) mesylate is an orally active combined 5-HT and dopamine receptor antagonist[1]. Ziprasidone mesylate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM) [1].
CAS Number
[185021-64-1]
Product Name Alternative
CP-88059 (mesylate)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ziprasidone-mesylate.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC2=C(CC(N2)=O)C=C1CCN(CC3)CCN3C4=NSC5=C4C=CC=C5.OS(=O)(C)=O
Molecular Formula
C22H25ClN4O4S2
Molecular Weight
509.04
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]H Rollema, et al. 5-HT (1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex. Biol Psychiatry. 2000 Aug 1;48 (3) :229-37.|[2]Zhi Su, et al. Block of hERG channel by ziprasidone: biophysical properties and molecular determinants. Biochem Pharmacol. 2006 Jan 12;71 (3) :278-86.|[3]Subin Park, et al. The effect of ziprasidone on body weight and energy expenditure in female rats. Metabolism. 2012 Jun;61 (6) :787-93.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT1 Receptor;5-HT2 Receptor; D2 Receptor; mLAG-3; α-1 microglobulin

Related Products

CatalogName
HY-14542-01Ziprasidone
HY-100649Hydroxy ziprasidone
HY-14542SZiprasidone-d8
HY-100648-01Keto Ziprasidone
HY-14542R-01Ziprasidone (Standard)
HY-14542A-01Ziprasidone (hydrochloride)
HY-14542ARZiprasidone (hydrochloride) (Standard)
HY-17407-01Ziprasidone (hydrochloride monohydrate)
HY-131255-01Ziprasidone amino acid
HY-17407R-01Ziprasidone (hydrochloride monohydrate) (Standard)

Alternative Products

CatalogName
MBS5806172Ziprasidone mesylate
MBS5806643Ziprasidone mesylate trihydrate
MBS577501Ziprasidone
sc-4706833-Oxo Ziprasidone (Ziprasidone Impurity B)
RM-Z161801-01Ziprasidone EP Impurity A; Ziprasidone USP Rc A
RM-Z161806-01Ziprasidone Sulfoxide
MBS3841773-01Ziprasidone hydrochloride
MBS5766923Keto Ziprasidone
319102Ziprasidone HCl
A15286-100Ziprasidone 100mg

Popular Products