Ziprasidone (Standard)

CAT: 0804-HY-14542R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-14542R-01Size:5 mg
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Description
Ziprasidone (Standard) is the analytical standard of Ziprasidone. This product is intended for research and analytical applications. Ziprasidone (CP-88059), an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist[1]. Ziprasidone mesylate trihydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM) [1].
CAS Number
[146939-27-7]
UNSPSC
12352100
Target
5-HT Receptor; Dopamine Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
ClC1=CC2=C(CC(N2)=O)C=C1CCN(CC3)CCN3C4=NSC5=C4C=CC=C5
Molecular Formula
C21H21ClN4OS
Molecular Weight
412.94
References & Citations
[1]Rollema H, et al. 5-HT (1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex. Biol Psychiatry. 2000;48 (3) :229-237.|[2]Zhi Su, et al. Block of hERG channel by ziprasidone: biophysical properties and molecular determinants. Biochem Pharmacol. 2006 Jan 12;71 (3) :278-86.|[3]Subin Park, et al. The effect of ziprasidone on body weight and energy expenditure in female rats. Metabolism. 2012 Jun;61 (6) :787-93.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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