BRD2889

CAT: 0804-HY-145413Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-145413Size:1 Each
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Description
BRD2889 is an analog of the alkaloid piperlongumine. BRD2889 is a robust modulator of the GSTP1-ISCU axis in pulmonary hypertension (PH) [1]. BRD2889 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[1415153-39-7]
UNSPSC
12352005
Target
Glutathione S-transferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd2889.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C(C=C1OC)/C=C/C(N2C(C(C#CC3=CC=C(C=C3)OC)=CCC2)=O)=O)OC
Molecular Formula
C26H25NO6
Molecular Weight
447.48
References & Citations
[1]Negi V, et al. Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension. Sci Adv. 2021;7 (43) :eabh3794.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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