BRD4884

CAT: 0804-HY-102083Size: 500 µgDry Ice: NoHazardous: No
CAT#:0804-HY-102083Size:500 µg
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Description
BRD4884 is a potent and brain-penetrant HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1090 nM for HDAC1, HDAC2, and HDAC3, respectively. BRD4884 can be used for the study of cognitive impairment[1].
CAS Number
[1404559-91-6]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/brd4884.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(C1CCOCC1)NC2=CC(C3=CC=C(F)C=C3)=CC=C2N
Molecular Formula
C18H19FN2O2
Molecular Weight
314.35
References & Citations
[1]Wagner FF, et al. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers. Chem Sci. 2015 Jan 1;6 (1) :804-815.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC2; HDAC3

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