TRPC5-IN-1

CAT: 0804-HY-145150-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-145150-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TRPC5-IN-1 (Compound 6j) is a selective TRPC5 inhibitor with 50.5 % Inhibition for TRPC5 at 3 μM. TRPC5-IN-1 can be used for the research of chronic kidney disease (CKD) [1].
CAS Number
[2265215-18-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/trpc5-in-1.html
Purity
98.97
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
N#CC1=CC=C(CN2C(NCC3=CC=CO3)=NC4=C2C=CC=C4)C=C1
Molecular Formula
C20H16N4O
Molecular Weight
328.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Sharma SH, et al. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorg Med Chem Lett. 2019 Jan 15;29 (2) :155-159.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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