TRPC5-IN-1

CAT:

804-HY-145150

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CAS Number: 2265215-18-5
UNSPSC Description: TRPC5-IN-1 (Compound 6j) is a selective TRPC5 inhibitor with 50.5 % Inhibition for TRPC5 at 3 μM. TRPC5-IN-1 can be used for the research of chronic kidney disease (CKD)[1].
Target Antigen: TRP Channel
Type: Reference compound
Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
Applications: Neuroscience-Neuromodulation
Field of Research: Metabolic Disease
Assay Protocol: https://www.medchemexpress.com/trpc5-in-1.html
Solubility: 10 mM in DMSO
Smiles: N#CC1=CC=C(CN2C(NCC3=CC=CO3)=NC4=C2C=CC=C4)C=C1
Molecular Weight: 328.37
References & Citations: [1]Sharma SH, et al. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorg Med Chem Lett. 2019 Jan 15;29(2):155-159.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-145150	TRPC5-IN-1
HY-144208	TRPC5-IN-3
HY-144205	TRPC5-IN-2
HY-144429	TRPC5-IN-4
HY-142030	TRPC5 modulator-1
HY-RS15108	TRPC5 Human Pre-designed siRNA Set A
HY-163546	HSV-1-IN-1
HY-163731-01	EGR-1-IN-1
HY-159569-04	TfR-1-IN-1
HY-159569-01	TfR-1-IN-1