TRPC5-IN-4

CAT:

804-HY-144429

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CAS Number: 2762315-39-7
UNSPSC Description: TRPC5-IN-4 is potent and safe TRPC inhibitor with IC50 value of 14.07 nM and 65 nM for TRPC5 and TRPC4, respectively. TRPC5-IN-4 shows no damage on the cellular component of liver and kidney. TRPC5-IN-4 can be used for the research of chronic kidney disease (CKD)[1].
Target Antigen: TRP Channel
Type: Reference compound
Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
Applications: Metabolism-protein/nucleotide metabolism
Field of Research: Metabolic Disease
Assay Protocol: https://www.medchemexpress.com/trpc5-in-4.html
Solubility: 10 mM in DMSO
Smiles: O=C1NC(C(N2CCC3=C(N=CN=C3OC4=C(C=C(C=C4)F)C(F)(F)F)C2)=C1Cl)=O
Molecular Weight: 442.75
References & Citations: [1]Zhang Z, Chen L, Tian H, et al. Discovery of pyrroledione analogs as potent transient receptor potential canonical channel 5 inhibitors. Bioorg Med Chem Lett. 2022;61:128612.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-144429	TRPC5-IN-4
HY-145150	TRPC5-IN-1
HY-144208	TRPC5-IN-3
HY-144205	TRPC5-IN-2
HY-142030	TRPC5 modulator-1
HY-RS15108	TRPC5 Human Pre-designed siRNA Set A
HY-135127-02	Dot1L-IN-4
HY-135127-01	Dot1L-IN-4
HY-151813-02	NNMT-IN-4
HY-151813-01	NNMT-IN-4