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NSC381467

CAT: 0804-HY-144444Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144444Size:1 Each
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Description
NSC381467 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK) . NSC381467 has strong antiproliferative activities. NSC381467 has the potential for the research of cancer diseases[1].
CAS Number
1033006-96-0
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc381467.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC2=C1C(C3=C(C4=C([C@H]([C@@H]3O)O)C=C(C=C4O)CO)C2=O)=O
Molecular Formula
C20H16O7
Molecular Weight
368.34
References & Citations
[1]Jiwacharoenchai N, et al. Discovery of potent antiproliferative agents from selected oxygen heterocycles as EGFR tyrosine kinase inhibitors from the U.S. National Cancer Institute database by in silico screening and bioactivity evaluation. Bioorg Med Chem Lett. 2022;58:128524.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19187103-01NSC381467

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