β-Lactamase-IN-7

β-Lactamase-IN-7

• CAS Number: 2419903-21-0
• UNSPSC Description: β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with Kis of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. β-Lactamase-IN-7 can effectively inhibit Klebsiella pneumoniae[1].
• Target Antigen: Bacterial; Beta-lactamase
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/β-lactamase-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: S=C1NN=C(C2=CC=CC=C2)N1CCSC3=CC=CC=C3
• Molecular Weight: 313.44
• References & Citations: [1]Legru A, et al. 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity. Eur J Med Chem. 2021;226:113873.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported