JAK-IN-18

JAK-IN-18

• CAS Number: 2247925-32-0
• UNSPSC Description: JAK-IN-18 is a potent inhibitor of JAK. JAK-IN-18 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases (extracted from patent WO2018204238A1, compound 1)[1].
• Target Antigen: JAK
• Type: Reference compound
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/jak-in-18.html
• Solubility: 10 mM in DMSO
• Smiles: FC1=CC(C2=CC(F)=C(O)C=C2CC)=CC3=C1C(C(N4)=NC5=C4CN(C(CN6CCOCC6)=O)CC5)=NN3
• Molecular Weight: 522.55
• References & Citations: [1]Paul R. Fatheree, et al. Fused imidazo-piperidine jak inhibitor compound. Patent WO2018204238A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported