Propargyl-PEG-amine

• Description :

  Propargyl-PEG-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• CAS Number :

  [956348-61-1]

• UNSPSC :

  12352211

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/propargyl-peg-amine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C#CCOCCOCCN.[n]

• Molecular Formula :

  (C2H4O) nC5H9NO

• References & Citations :

  [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PEG Linkers