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Cap-dependent endonuclease-IN-9

CAT: 0804-HY-143755Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143755Size:1 Each
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Description
Cap-dependent endonuclease-IN-9 is a potent inhibitor of cap-dependent endonuclease (CEN) . Not only can Cap-dependent endonuclease-IN-9 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-9 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent CN112521386A, compound VI-1) [1].
CAS Number
2631005-84-8
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cap-dependent-endonuclease-in-9.html
Solubility
10 mM in DMSO
Smiles
O=C1N2[C@@H](CC3=C(N=CO3)C2)N([C@H]4C5=CC=C(F)C(F)=C5CSC6=CC=CC=C64)N7C1=C(C(C=C7)=O)OCOC(OC)=O
Molecular Formula
C29H22F2N4O7S
Molecular Weight
608.57
References & Citations
[1]Yutian Zhou, et al. Polycyclic pyridone compounds with antiviral effects and their pharmaceutical compositions and uses. Patent CN112521386A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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