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Cap-dependent endonuclease-IN-2

CAT: 0804-HY-143743Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143743Size:1 Each
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Description
Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent endonuclease (CEN) . Not only can Cap-dependent endonuclease-IN-2 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-2 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent WO2019052565A1, compound 28) [1].
CAS Number
2303917-78-2
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cap-dependent-endonuclease-in-2.html
Solubility
10 mM in DMSO
Smiles
COC(OCOC1=C2N(C=CC1=O)N([C@@]3([H])N(CCOC3)C2=O)[C@@]4([H])C5=CC=C(F)C=C5C6=C(SC=C6)C7=CC=CC=C74)=O
Molecular Formula
C30H24FN3O7S
Molecular Weight
589.59
References & Citations
[1]Changhua Tang, et al. Influenza virus replication inhibitors and their uses. Patent WO2019052565A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported