Cap-dependent endonuclease-IN-2

Cap-dependent endonuclease-IN-2

• CAS Number: 2303917-78-2
• UNSPSC Description: Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-2 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-2 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent WO2019052565A1, compound 28)[1].
• Target Antigen: Influenza Virus
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/cap-dependent-endonuclease-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: COC(OCOC1=C2N(C=CC1=O)N([C@@]3([H])N(CCOC3)C2=O)[C@@]4([H])C5=CC=C(F)C=C5C6=C(SC=C6)C7=CC=CC=C74)=O
• Molecular Weight: 589.59
• References & Citations: [1]Changhua Tang, et al. Influenza virus replication inhibitors and their uses. Patent WO2019052565A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported