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AKT-IN-8

CAT: 0804-HY-143611Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143611Size:1 Each
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Description
AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively[1].
CAS Number
2654026-13-6
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/akt-in-8.html
Solubility
10 mM in DMSO
Smiles
OCC[C@@H](C1=CC=C(C=C1)Cl)NC([C@@]2(C[C@]3([H])N(CC2)C4=C5C(OC3)=CN=C5N=CN4)N)=O
Molecular Formula
C22H25ClN6O3
Molecular Weight
456.93
References & Citations
[1]Fused tetracyclic derivative, preparation method therefor, and medical use thereof. WO2021121276A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Akt1; Akt2; Akt3

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