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MALT1-IN-8

CAT: 0804-HY-143426Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143426Size:1 Each
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Description
MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8) [1].
CAS Number
2244109-29-1
UNSPSC
12352005
Target
MALT1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/malt1-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C(C4CC4)C5=CC(Cl)=CC=C5N=C3
Molecular Formula
C20H15Cl2N7O
Molecular Weight
440.29
References & Citations
[1]Nathanael S. Gray, et al. Inhibitors of malt1 and uses thereof. WO2018165385A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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