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COTI-219

CAT: 0804-HY-143359Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143359Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
COTI-219 is an orally active inhibitor of KRAS. COTI-219 has antitumor activity[1].
CAS Number
1039455-85-0
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/coti-219.html
Solubility
10 mM in DMSO
Smiles
S=C(N1CCN(CC1)C)N/N=C2C3=C(C4=CC=CN=C\24)C=CC=N3
Molecular Formula
C17H18N6S
Molecular Weight
338.43
References & Citations
[1]Sandra E., et al. Treatment of kras mutant cancers. WO2022109307A1.2022-05-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported