COTI-219

• UNSPSC Description:

  COTI-219 is an orally active inhibitor of KRAS. COTI-219 has antitumor activity[1].

• Target Antigen:

  Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/coti-219.html

• Solubility:

  10 mM in DMSO

• Smiles:

  S=C(N1CCN(CC1)C)N/N=C2C3=C(C4=CC=CN=C\24)C=CC=N3

• Molecular Weight:

  338.43

• References & Citations:

  [1]Sandra E., et al. Treatment of kras mutant cancers. WO2022109307A1.2022-05-27.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1039455-85-0