COTI-219

• Description :

  COTI-219 is an orally active inhibitor of KRAS. COTI-219 has antitumor activity[1].

• UNSPSC :

  12352005

• Target :

  Ras

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/coti-219.html

• Solubility :

  10 mM in DMSO

• Smiles :

  S=C(N1CCN(CC1)C)N/N=C2C3=C(C4=CC=CN=C\24)C=CC=N3

• Molecular Formula :

  C17H18N6S

• Molecular Weight :

  338.43

• References & Citations :

  [1]Sandra E., et al. Treatment of kras mutant cancers. WO2022109307A1.2022-05-27.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1039455-85-0]