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CEase-IN-1

CAT: 0804-HY-143252Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143252Size:1 Each
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Description
CEase-IN-1 (Compound A1H3) is a potent and selective cholesterol esterase (CEase) inhibitor with an IC50 of 0.36 μM. CEase-IN-1 can be used for the research of hypercholesterolemia[1].
CAS Number
2985688-68-2
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cease-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(COC1=CC=C(C(F)(F)F)C=C1)N/N=C/CCC
Molecular Formula
C13H15F3N2O2
Molecular Weight
288.27
References & Citations
[1]Zhao S, et al. Identification and synthesis of selective cholesterol esterase inhibitor using dynamic combinatorial chemistry. Bioorg Chem. 2022 Feb;119:105520.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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Alternative Products

CatalogName
GTR19187892-01CEase-IN-1
210094-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) discontinued
MBS6411210-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) (HRP)
MBS6411209-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) (FITC)
MBS6411207-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) (APC)
MBS6411206-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) (AP)
MBS6411216-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) (PE)
MBS6411208-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) (Biotin)
MBS6411215-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) (MaxLight 750)
MBS6411211-01CEL (Carboxyl Ester Lipase, BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8) (MaxLight 405)

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