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TP0586352

CAT: 0804-HY-142619Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142619Size:1 Each
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Description
TP0586352 is a LpxC inhibitor that is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk. TP0586352 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
2427626-11-5
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tp0586352.html
Solubility
10 mM in DMSO
Smiles
NC[C@@H](N1C([C@@H](O)C)=NC=C1)C2=NOC(C(C=C3)=CC=C3C#C[C@H]4[C@@]5([H])[C@]4([H])CN(C5)C[C@@H](O)C)=C2
Molecular Formula
C26H31N5O3
Molecular Weight
461.56
References & Citations
[1]Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021 Jan 15;30:115964.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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