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Efalizumab

CAT: 0804-HY-P9947-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P9947-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Efalizumab is a targeted T cell modulator, and is a humanized monoclonal antibody of CD11a, the α subunit of LFA-1. Efalizumab inhibits T cell activation, cutaneous T cell trafficking, and T cell adhesion to keratinocytes, can be used for plaque psoriasis research[1].
CAS Number
214745-43-4
UNSPSC
12352203
Target
Integrin
Type
Inhibitory Antibodies
Related Pathways
Cytoskeleton
Applications
COVID-19-anti-virus
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/efalizumab.html
Purity
98.77
Solubility
H2O
Smiles
[Efalizumab]
Molecular Weight
(146.14 kDa)
References & Citations
[1]Leonardi CL. Efalizumab: an overview. J Am Acad Dermatol. 2003 Aug;49 (2 Suppl) :S98-104. |[2]Berger JR, et al. Monoclonal antibodies and progressive multifocal leukoencephalopathy. MAbs. 2009 Nov-Dec;1 (6) :583-9. |[3]Koszik F, et al. Efalizumab modulates T cell function both in vivo and in vitro. J Dermatol Sci. 2010 Dec;60 (3) :159-66.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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