NSD3-IN-3

• Description:

  NSD3-IN-3 is a potent NSD3 inhibtor with an IC50 value of 1.86 μM. NSD3-IN-3 has anticancer activity and significantly inhibits the growth and proliferation of non-small cell lung cancer cell line H460[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nsd3-in-3.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  S=C1NC2=C(N)N=CN=C2N1CCOC3=CC=C(OCC)C=C3

• Molecular Formula:

  C15H17N5O2S

• Molecular Weight:

  331.39

• References & Citations:

  [1]Kong Ren, et al. Application of compound B2 as histone methyltransferase NSD3 inhibitor: China, CN109223795[P].2019-01-18.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [445416-12-6]