PRT543

CAT: 0804-HY-141876Size: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-141876Size:1 Each

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Description

PRT543 is a PRMT5 inhibitor to research cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.

CAS Number

[2278356-90-2]

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/prmt5-in-14.html

Solubility

10 mM in DMSO

Smiles

O[C@@]1(C)[C@@H](O)[C@H](N2C3=NC=NC(N)=C3C=C2)O[C@@H]1[C@H](O)C4=CC=C(Cl)C(Cl)=C4

Molecular Formula

C18H18Cl2N4O4

Molecular Weight

425.27

References & Citations

[1]Machacek M, et al. Prmt5 inhibitors. WO2020033285A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PRMT5

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